Tetrahedron

The behavior of amides of N-acylamino acids toward aniline and substituted anilines under papain catalysis

JL Abernethy, FG Howell, A Ledesma, D Doose…

文献索引：Abernethy,J.L. et al. Tetrahedron, 1975 , vol. 31, p. 2659 - 2662

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被引用次数: 4

摘要

Resolution of z-dl-alanine amide has been achieved through papain-catalyzed reactions with aniline, the three anisidines, the three aminophenols and the three fluoroanilines. Most of the resultant anilides displayed better than a 95% resolution of the racemic amide. The four methyl esters of hippuric acid, z-glycine, zl-alanine and z-dl-alanine were prepared by means of a recently reported catalytic dehydrator in the presence of excess dry methanol. ...