Abstract Several sulfenamide derivatives were designed as possible acetylcholinesterase (AChE) inhibitors. New sulfenamides were synthesized and proved to be stable under the physiological conditions used in the enzymatic assays. N-benzyl-2- benzoxazolylsulfenamide (8) and N-benzyl-2-benzimidazolylsulfenamide (9) revealed anti- AChE activity with IC 50 values of 0.6 and 0.8 μM, respectively, values of the same ...
