C. S. Rooney,* D. W. Cochran,* C. Ziegler, and EJ Cragoe, Jr. ... HWR Williams Merck Frosst Canada Znc., Pointe Claire/Dorual, Quebec, Canada H9R 4P8 Received June 17, 1983 ... Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania 19486 ... 5-Phenyl- and 5-thiazolyl-4-hydroxy-3(2iY)-isothiazolone 1,l-dioxide derivatives have been prepared by base-catalyzed cyclocondensation of diethyl oxalate with an arylmethanesulfonamide, as ...