Facile synthesis of 2-phenylquinoline-4-carboxamide derivatives with variant structural features

…, MI Hossain, Y Okamoto, T Nagamatsu…

文献索引：Islam, Rafiqul; Hossain, Md. Imran; Okamoto, Yoshinari; Nagamatsu, Tomohisa; Anraku, Kensaku; Okawara, Tadashi Heterocycles, 2014 , vol. 89, # 3 p. 693 - 708

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摘要

Abstract The quinoline scaffold is an important class of heterocyclic compounds that possesses diverse chemotherapeutic activities. Thus, the 2-phenylquinoline-4-carboxamide derivatives containing a variety of moieties, such as 2-(2-furanyl)-1, 3, 4-oxadiazole, N-(2- methylphenyl)-4-(3-pyridinyl)-2-pyrimidinamine, 4, 4′-bithiazole, purine, adamantine and resorcinol, have been designed and synthesized via Suzuki coupling, acid-base coupling ...