1, 3-Dimethyl-3-acyltriazenes: Synthesis and chemistry of a novel class of biological methylating agents

RH Smith Jr, AF Mehl, A Hicks…

文献索引：Smith Jr.; Mehl; Hicks; et al. Journal of Organic Chemistry, 1986 , vol. 51, # 20 p. 3751 - 3757

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被引用次数: 32

摘要

The synthesis and hydrolytic decomposition of 1, 3-dimethyl-3-(diethoxyphosphinyl) triazene (DMP), 1, 3-di-methyl-3-carboethoxytriazene (DMC), 1, 3-dimethyl-3-acetyltriazene (DMA), and 1, 3-dimethyl-3-(N-methyl-carbamoy1) triazene (DMM) are described. The kinetics of hydrolysis of DMP and DMC were investigated in aqueous buffers as a function of pH. DMP was found to be subject to acid catalysis up to pH 4.5 but then followed uncatalyzed ...