Synthesis and antimicrobial evaluation of some chalcones and their derived pyrazoles, pyrazolines, isoxazolines, and 5, 6-dihydropyrimidine-2-(1H)-thiones

AH Adel, ES Ahmed, MAM Hawata, ER Kasem…

文献索引：Abdel-Rahman, Adel A.-H.; Abdel-Megied, Ahmed E.-S.; Hawata, Mohamed A. M.; Kasem, Eman R.; Shabaan, Mohamed T. Monatshefte fur Chemie, 2007 , vol. 138, # 9 p. 889 - 897

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被引用次数: 48

摘要

Summary. Chalcones were synthesized by a base catalyzed Claisen-Schmidt condensation reaction. Bromination of chalcones afforded the dibromo derivatives. Monobromo derivatives could be obtained by treating the corresponding dibromochalcones with dry benzene in the presence of triethylamine. Pyrazole derivatives were obtained by refluxing of dibromochalcones with phenylhydrazine or 2, 4-dinitrophenylhydrazine in dry pyridine. ...