Natural product research

Synthesis, phytotoxic, cytotoxic, acetylcholinesterase and butrylcholinesterase activities of N, N′-diaryl unsymmetrically substituted thioureas

S Begum, MI Choudhary, KM Khan

文献索引：Begum, Saeedan; Choudhary, M. Iqbal; Khan, Khalid M. Natural Product Research, 2009 , vol. 23, # 18 p. 1719 - 1730

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被引用次数: 3

摘要

Fourteen N, N′-diaryl unsymmetrically substituted thioureas were synthesised and their cytotoxic (in vitro), phytotoxic (in vitro), acetylcholinesterase and butrylcholinesterase activities were determined. Thiourea 16 exhibited high, and 1 and 3 showed significant phytotoxic activity. Thioureas 1, 3, 4, 6 and 10 showed significant activity and 2, 6 and 7 indicated moderate cytotoxic activities. Compound 12 exhibited butrylcholinesterase ...