Bioorganic & medicinal chemistry

Ring-deactivated hydroxymethylpyrroles as inhibitors of α-chymotrypsin

AD Abell, BK Nabbs

文献索引：Abell, Andrew D.; Nabbs, Brent K. Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 621 - 628

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被引用次数: 12

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... N-Acyl and N-sulfonylhydroxymetyhylpyrroles have been synthesised and shown to inhibit α-chymotrypsin. A hydrophobic group in the N-substituent has been shown to be required for activity. ... We have an ongoing interest in the design of inhibitors of serine proteases ...