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… compounds: XVIII. 5-Arylfuran-2-carboxylic acids and their application in the synthesis of 1, 2, 4-thiadiazole, 1, 3, 4-oxadiazole, and [1, 2, 4] triazolo [3, 4-b][1, 3, 4] …

YI Gorak, ND Obushak, VS Matiichuk…

文献索引:Gorak; Obushak; Matiichuk; Lytvyn Russian Journal of Organic Chemistry, 2009 , vol. 45, # 4 p. 541 - 550

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被引用次数: 14

摘要

Abstract Arylation of furan-2-carboxylic acid or its methyl ester with arenediazonium chlorides in the presence of copper (II) chloride gave the corresponding 5-arylfuran-2- carboxylic acids or methyl 5-arylfuran-2-carboxylates. 5-Arylfuran-2-carbonyl chlorides reacted with potassium thiocyanate and then with 5-methyl-1, 2-oxazol-3-amine to give 5- aryl-N-[3-(2-oxopropyl)-1, 2, 4-thiadiazol-5-yl] furan-2-carboxamides as a result of ...

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