Bis-arylsulfonamide Derivatives of 2-Amino-5 (6)-(4-aminophenylthio) benzimidazole

VS Pilyugin, AN Mikhailyuk, VM Kosareva

文献索引：Pilyugin; Mikhailyuk; Kosareva Russian Journal of Organic Chemistry, 2002 , vol. 38, # 12 p. 1782 - 1789

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被引用次数: 1

摘要

A large number of methyl 5(6)-(4-aminophenoxy)- and 5(6)-(4-aminophenylthio)-2-benzimidazolylcarba - mate derivatives exhibit high antihelminthic activity [1316]. Unfortunately, most of them possess embryo- toxic and teratogenic properties which restrict their application in medical practice. We have developed a procedure for preparation of new bis-arylsulfamide derivatives of 2-amino-5(6)- (4-aminophenylthio)benzimidazole with the goal of studying their ...