Tetrahedron

Semisynthetic derivatives of quassin

CC Lang'at, RA Watt, I Toth, JD Phillipson

文献索引：Lang'at, Caroline C.; Watt, Robert A.; Toth, Istvan; Phillipson, J. David Tetrahedron, 1998 , vol. 54, # 24 p. 6841 - 6856

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被引用次数: 4

摘要

The natural product quassin has been modified in order to produce compounds with potential antimalarial action. The modifications include demethylation, reduction of the keto function, esterification with simple organic acids and-to enhance the uptake through the biological barriers and increase the stability of the compounds-with lipoamino acids.