Synthesis, spectral, crystal and antimicrobial studies of biologically potent oxime ethers of nitrogen, oxygen and sulfur heterocycles

P Parthiban, G Aridoss, P Rathika, V Ramkumar…

文献索引：Parthiban, Paramasivam; Aridoss, Gopalakrishnan; Rathika, Paramasivam; Ramkumar, Venkatachalam; Kabilan, Senthamaraikannan Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 11 p. 2981 - 2985

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被引用次数: 43

摘要

Three series of oxime ethers viz, 2, 6-diarylpiperidin-4-one O-benzyloximes 5a–o, 2, 6- diaryltetrahydropyran-4-one O-benzyloximes 7a–e and 2, 6-diaryltetrahydrothiopyran-4-one O-benzyloximes 11a–b and 12a–c were synthesized and stereochemistry is established by their spectral and single crystal analysis. A SAR study has been carried out for the above oxime ethers against a panel of antibacterial (Pseudomonas aeruginosa, Staphylococcus ...