Synthesis of new fused isoquinolines via reissert compounds

…, C Bender, B Ziemer, J Liebscher

文献索引：Fuchs, Christian; Bender, Christoph; Ziemer, Burkhard; Liebscher, Juergen Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 6 p. 1651 - 1658

全文：HTML全文

被引用次数: 12

摘要

Reissert compounds, ie. N-acyl-1-cyano-1, 2-dihydroisoquinolines, have been known for more than 100 years [1]. They are formed from isoquinolines or similar N-6-ring- heterocycles, acyl chlorides or acid anhydrides and cyanide via intermediate N-acyliminium salts. This reaction was originally used to transform acyl chlorides into aldehydes by final acid hydrolysis of the Reissert compounds. Following this, Reissert compounds were also ...