Synthesis, characterization and antimicrobial activity of some new 1-(fluorobenzoyl)-3-(fluorophenyl) thioureas

A Saeed, U Shaheen, A Hameed, SZH Naqvi

文献索引：Saeed, Aamer; Shaheen, Uzma; Hameed; Naqvi, S.Z. Haider Journal of Fluorine Chemistry, 2009 , vol. 130, # 11 p. 1028 - 1034

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被引用次数: 55

摘要

Synthesis of a variety of new 1-(isomeric fluorobenzoyl)-3-(isomeric fluorophenyl) thioureas (1a–t) was accomplished in two steps. The synthetic route involves the reaction of equimolar quantities of isomeric fluorobenzoyl chlorides with potassium thiocyanate in anhydrous acetone to afford the corresponding isothiocyantes in situ, followed by treatment with equimolar quantities of isomeric fluoroanilines. All of the synthesized compounds (1a–t) ...