Synthesis and biological activities of some new fluorinated coumarins and 1-aza coumarins

RG Kalkhambkar, GM Kulkarni, CM Kamanavalli…

文献索引：Kalkhambkar, Rajesh G.; Kulkarni, Geeta M.; Kamanavalli, Chandrappa M.; Premkumar; Asdaq; Sun, Chung Ming European Journal of Medicinal Chemistry, 2008 , vol. 43, # 10 p. 2178 - 2188

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被引用次数: 64

摘要

A series of new fluorinated coumarins and 1-aza coumarins have been synthesized and the presence of fluorine in these molecules and its effect on their anti-microbial, anti- inflammatory and analgesic activities are discussed. The results of bioassay showed that these newly synthesized compounds containing fluorine exhibit moderate analgesic and excellent anti-inflammatory and potential anti-bacterial and anti-fungal activities, ...