Journal of heterocyclic chemistry

Some observations concerning the lactonization of 3??aroylpropionic acids

A Tsolomitis, C Sandris

文献索引：Tsolomitis, A.; Sandris, C. Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1545 - 1548

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被引用次数: 18

摘要

Abstract The ease of lactonization of the γ-keto acids ArCOCH 2 CH 2 COOH is shown to depend on the nature of the aryl group: the presence of electron-releasing substituents on the aryl group results in a more rapid reaction as compared to the presence of electron- withdrawing substituents. The case of this cyclodehydration reaction is also shown to depend on the reagent used: acetic anhydride-sulfuric acid is a more drastic reagent than ...