Synlett

Synthesis of Epothilones: Stereoselective Routes to Epothilone B

D Schinzer, A Bauer, J Schieber

文献索引：Schinzer, Dieter; Bauer, Armin; Schieber, Jennifer Synlett, 1998 , # 8 p. 861 - 864

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被引用次数: 22

摘要

Abstract: In connection with our studies of the total syntheses of epothilones we report our efforts on the syntheses of epothilone B using a macro-lactonization and a metathesis approach. Key reaction for the solution of the acyclic stereoselection is a stereoselective aldol reaction.