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Palladium-catalyzed oxidative Heck coupling reaction for direct synthesis of 4-arylcoumarins using coumarins and arylboronic acids

Y Li, Z Qi, H Wang, X Fu, C Duan

文献索引:Li, Yaming; Qi, Zisong; Wang, Huifeng; Fu, Xinmei; Duan, Chunying Journal of Organic Chemistry, 2012 , vol. 77, # 4 p. 2053 - 2057

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被引用次数: 63

摘要

An efficient protocol for the direct synthesis of 4-arylcoumarins via palladium-catalyzed oxidative Heck coupling reaction of coumarins and arylboronic acids was developed. 4- Arylcoumarins were obtained in moderate to excellent yields, and the reaction also showed tolerance toward functional groups such as hydro, methoxy, diethylamino, nitro, and chloro groups.