J. Chem. Soc. Pakistan

Spectrophotometric Determination of pK (a)'s of 1-Hydroxybenzotriazole and Oxime Derivatives in 95% Acetonitrile-Water

MF Fathalla, SN Khattab

文献索引：Fathalla, Magda Fouad; Khattab, Sherine Nabil Journal of the Chemical Society of Pakistan, 2011 , vol. 33, # 3 p. 324 - 332

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被引用次数: 14

摘要

Summary: 1-hydroxybenzotriazole derivatives are used with carbodiimide as additives to generate active esters during peptide bond formation. They are also used as additives during the peptide bond formation. Dissociation constants of the 1-hdroxybenzotriazole (HOBt) and its derivatives, 1-hydroxy-6-chlorobenzotriazole, 1-hydroxy-6- trifluoromethylbenzotriazole, 1-hydroxy-6-nitrobenzotriazole were determined ...