Journal of Heterocyclic Chemistry

The synthesis and ring opening of N??substituted??2??oxo??6??azaspiro [2, 5] octanes

FD Popp, RF Watts

文献索引：Popp,F.D.; Watts,R.F. Journal of Heterocyclic Chemistry, 1978 , vol. 15, p. 675 - 676

全文：HTML全文

被引用次数: 7

摘要

Abstract N-Substituted-4-piperidones have been reacted with trimethyl sulfoxonium iodide to give the title compounds. These undergo ring opening with lithium aluminum hydride- aluminum chloride to give piperidine-4-methanols which were converted to the chloromethylpiperidines.