Calcium??Catalyzed Direct Amination of π??Activated Alcohols

S Haubenreisser, M Niggemann

文献索引：Haubenreisser, Stefan; Niggemann, Meike Advanced Synthesis and Catalysis, 2011 , vol. 353, # 2-3 p. 469 - 474

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被引用次数: 32

摘要

Abstract A calcium-catalyzed direct amination of π-activated alcohols with different nitrogen nucleophiles under very mild reaction conditions is presented. The high reactivity of the calcium catalyst allows for an efficient conversion of secondary and tertiary benzylic and allylic as well as tertiary propargylic alcohols. Nitrogen nucleophiles such as carbamates, tosylamides and anilines are readily alkylated at room temperature.