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Design of integrated fluorescent estrogens: the second donor effect on absorption, fluorescence, and ground-state molecular orbital properties of trans-4, 4'- …

GM Anstead, JA Katzenellenbogen

文献索引:Anstead, Gregory M.; Katzenellenbogen, John A. Journal of Physical Chemistry, 1990 , vol. 94, # 4 p. 1328 - 1334

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被引用次数: 11

摘要

In the design of inherently fluorescent ligands for the estrogen receptor, biological constraints limit to hydroxyl the functional groups that can be utilized as electron donors. In an attempt to optimize the fluorescent properties of such probes, we have studied the effect that a second alkoxy donor has on the fluorescence properties of two systems, peripherally located in a nitro-substituted diarylindene, and centrally located in a nitrostilbene. The ...