Carcinogenic and adrenocorticolytic derivatives of benz [a] anthracene

J Pataki, C Duguid, PW Rabideau…

文献索引：Pataki,J. et al. Journal of Medicinal Chemistry, 1971 , vol. 14, # 10 p. 940 - 945

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被引用次数: 14

摘要

A> erieh of dimet, hyl, trimethyl, hydrosymethyl, atid formyl derivatives of benz [a] anthracene structurally i, elated to i he cai, cinogenic 7-methy1-, 12-methyl-, and 7, 12-dimetjhylbenz [a] anthracene and to the adreno-(~ oi. ticolytic Th~ d~ osymethyl-l~-meth~ lbenz [a] aiithrac~ e~ ie were synthesized.> le; irtbstjitution outside the" criticnl" regioii (i,~., the 6, 7, X, and 12 pwitions) was shown to block sarcomagenic, activity when iii the 1, 2,:!, 4, aiiti 5 positioiis ( ...