Tetrachlorosilane-Zinc Chloride as a New Potent Binary Reagent for One-Pot, Three-Component Synthesis of Mannich-Type Products
…, E Abdel-Galil, EM Kandeel, WM Basyouni…
文献索引：Badawy, Doria S.; Abdel-Galil, Ebrahim; Kandeel, Ezzat M.; Basyouni, Wahid M.; Khatab, Tamer K. Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 11 p. 2799 - 2812
A combination of tetrachlorosilane and zinc chloride in dichloromethane as an efficient and ambient binary reagent to promote a one-pot amidoalkylation reaction of enolizable ketones, aromatic aldehydes with acetonitriles, or benzonitrile have been developed. The newly synthesized β-acetamidoketones 3 and β-benzamidoketones 5 were obtained in good yields.
