Synthesis of 5??lodo??and 5??nitro??3??indolyl phosphates as cytochemical substrates for acid phosphatase

DJ Rabiger, MY Chang, S Matsukawa…

文献索引：Rabiger,D.J. et al. Journal of Heterocyclic Chemistry, 1970 , vol. 7, p. 307 - 311

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被引用次数: 8

摘要

Abstract The synthesis of 5-iodo-3-indolyl and 5-nitro-3-indolyl phosphate for cytochemical demonstration of acid phosphatase is reported. Enzymatic hydrolysis of these compounds liberates the corresponding indoxyl which is oxidized to the substituted indigo at an acid pH. In contrast, the 5-bromo and the unsubstituted indoxyl are not oxidized readily at an acid pH. Comparison of the UV and visible, spectra of the disubstituted indigo has offered a partial ...