Abstract: The combination of N-chlorodiisopropylamine and triphenylphosphine (1) was exploited as a new method for chlorination of the hydroxyl group on the nucleosides. A possible mechanism involving an oxyphosphonium intermediate 2a and a phosphorane
![1-[5-(chloromethyl)-3,4-dihydroxy-oxolan-2-yl]pyrimidine-2,4-dione结构式](https://image.chemsrc.com/caspic/085/19556-54-8.png)