Tetrahedron Letters

Ultrasound in enzymatic resolution of ethyl 3-hydroxy-3-phenylpropanoate

CMR Ribeiro, EN Passaroto, ECS Brenelli

文献索引：Ribeiro, Carlos Magno R.; Passaroto, Elisa N.; Brenelli, Eugenia C.S. Tetrahedron Letters, 2001 , vol. 42, # 37 p. 6477 - 6479

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被引用次数: 50

摘要

The enzymatic hydrolysis of ethyl-3-hydroxy-3-phenylpropanoate using ultrasound bath and PCL, PLE and CRL enzymes was studied. The application of ultrasound bath led to an appreciative decrease in the reaction time of enzymatic hydrolysis without a significant change in the yield or enantiomeric excess of reaction products, when compared with the use of magnet stirring.