Abstract In a model system of initiated oxidation of methyl oleate, the antioxidant activities of 3-hydroxy-2-ethyl-6-methylpyridinesuccinate (mexidol) and bis [3-(3, 5-di-tert-butyl-4- hydroxyphenyl) propyl] disulfide (SO-4) were studied and compared with those of α- tocopherol and 1-hydroxy-2, 6-di-tert-butyl-4-methylbenzene (dibunol). A linear pattern of dependence of the inhibitory effect on the concentration of compounds was established. ...