Unusual behavior in the reactivity of 5-substituted-1H-tetrazoles in a resistively heated microreactor

…, T Razzaq, W Goessler, DM Roberge…

文献索引：Gutmann, Bernhard; Glasnov, Toma N.; Razzaq, Tahseen; Goessler, Walter; Roberge, Dominique M.; Kappe, C. Oliver Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 503 - 517

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被引用次数: 13

摘要

Abstract The decomposition of 5-benzhydryl-1H-tetrazole in an N-methyl-2- pyrrolidone/acetic acid/water mixture was investigated under a variety of high-temperature reaction conditions. Employing a sealed Pyrex glass vial and batch microwave conditions at 240 C, the tetrazole is comparatively stable and complete decomposition to diphenylmethane requires more than 8 h. Similar kinetic data were obtained in ...