Journal of Medicinal Chemistry

The synthesis of some acidic amino acids possessing neuropharmacological activity

JC Watkins

文献索引：Watkins,J.C. Journal of Medicinal and Pharmaceutical Chemistry, 1962 , vol. 5, p. 1187 - 1199

全文：HTML全文

被引用次数: 66

摘要

The observation that L-aspartic and L-glutamic acids excite mammalian nerve cells and cause contraction of crust, acean led to an ext'ensive survey of the actions of related substances on mammalian and toad spinal neurone~.~-~ It'was found that N-methyl-DL- aspartic acid was considerably more potent, both on