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Journal of fluorine chemistry

Synthesis of novel fluorobenzofuroxans by oxidation of anilines and thermal cyclization of arylazides

S Leyva, V Castanedo, E Leyva

文献索引:Leyva, Socorro; Castanedo, Victor; Leyva, Elisa Journal of Fluorine Chemistry, 2003 , vol. 121, # 2 p. 171 - 175

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被引用次数: 19

摘要

The synthesis of several fluorobenzofuroxans by oxidation of fluoroanilines and thermal cyclization of fluoroarylazides is presented. The fluorobenzofuroxans prepared in this study presented tautomerism as evidenced by their NMR data. Benzofuroxans in general have biological activity and are synthetic intermediates for the preparation of several compounds with important pharmaceutical applications.