Tetrahedron letters

Design of a C 2-symmetric chiral pyrrolidine-based amino sulfonamide: application to anti-selective direct asymmetric Mannich reactions

T Kano, Y Hato, K Maruoka

文献索引：Kano, Taichi; Hato, Yoshio; Maruoka, Keiji Tetrahedron Letters, 2006 , vol. 47, # 48 p. 8467 - 8469

全文：HTML全文

被引用次数: 40

摘要

The development of highly stereoselective asymmetric reactions using organocatalysts has become a research area of great importance, and a number of new organocatalysts have been devised for this purpose. 1 Accordingly, we already designed several binaphthyl-based secondary amine catalysts for aldol and other reactions involving enamine intermediates in their transition state. 2 Among them, chiral binaphthyl-based amino sulfonamide (S)-1 showed excellent ...