A Domino Approach (Hydrolysis/Dehydrohalogenation/Heck Coupling) for the Synthesis of Styrene Sulfonate Salts
GKS Prakash, PV Jog, HS Krishnan…
文献索引：Prakash, G. K. Surya; Jog, Parag V.; Krishnan, Hema S.; Olah, George A. Journal of the American Chemical Society, 2011 , vol. 133, # 7 p. 2140 - 2143
A domino approach of hydrolysis/dehydrohalogenation/Heck coupling was used to synthesize styrene sulfonate salts from iodoarenes and chloroethanesulfonyl chloride in good to excellent yields. Methodology was applicable for heterocyclic as well as disubstituted iodoarenes. Some of the key features of this synthetic methodology include the use of phosphine free catalytic system, water as an environmentally friendly solvent, short ...
