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Tetrahedron

Synthesis of cyclophospho-glucoses and glucitols

EJ Amigues, ML Greenberg, S Ju, Y Chen, ME Migaud

文献索引:Amigues; Greenberg; Ju; Chen; Migaud Tetrahedron, 2007 , vol. 63, # 40 p. 10042 - 10053

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被引用次数: 11

摘要

The syntheses of cyclophosphodiesters of 5-C-(hydroxymethyl)-hexoses and hexitols and of 6-C-(hydroxymethyl)-hexoses are reported, along with that of 6-deoxy-gluco-heptose 7- phosphate. These compounds proved to be reasonable substrate mimics and show inhibitory activity against human d-myo-inositol 3-phosphate synthase.