Enantioselective synthesis of phosphinyl peptidomimetics via an asymmetric Michael reaction of phosphinic acids with acrylate derivatives

X Liu, XE Hu, X Tian, A Mazur, FH Ebetino

文献索引：Lui, Xuewei; Hu, Eric; Tian, Xinrong; Mazur, Adam; Ebetino, Frank H. Journal of Organometallic Chemistry, 2002 , vol. 646, # 1-2 p. 212 - 222

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被引用次数: 50

摘要

Asymmetric Michael reaction of phosphinic or aminophosphinic acids with acrylate derivatives afforded phosphinyl dipeptidomimetics in excellent yields (> 90%). Chiral induction of substituents at the α-position of acrylate derivatives of Evans oxazolidinone ...