2, 3-Pyridine annulation. The enantioselective synthesis of an aldose reductase inhibitor
…, SW Goldstein, SL Pezzullo, GJ Quallich…
文献索引：Murtiashaw, Charles W.; Breitenbach, Ralph; Goldstein, Steven W.; Pezullo, Susan L.; Quallich, George J.; Sarges, Reinhard Journal of Organic Chemistry, 1992 , vol. 57, # 6 p. 1930 - 1933
This present methodology, therefore, appears to be novel and has greater synthetic utility than the procedures available thus far, since the easily available permanganate ion has been utilized to obtain some not 80 easily acceasible 5&6@-epoxides of AS-unsaturated steroids in high yields under very mild reaction conditions. The study of the mechanism of this reaction and the origin of ita high stereoselectivity are presently under investigation.
