Journal of the Chemical Society C: Organic

The synthesis of pyrido [4, 3-d] pyrimidin-4 (3 H)-ones from 4-amino-nicotinic acid

AG Ismail, DG Wibberley

文献索引：Ismail,A.G.; Wibberley,D.G. Journal of the Chemical Society [Section] C: Organic, 1967 , p. 2613 - 2617

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被引用次数: 7

摘要

Treatment of either a pyrido [4, 3-d][1, 3] oxazin-4-one or an ethyl 4-amidonicotinate with amines yields a 4-amidonicotinamide which may be cyclised by longer contact with the amine, or by heat, to give a pyrido [4, 3-d]-pyrimidin-4 (3H)-one. Some typical infrared and nuclear magnetic resonance spectra are discussed.