Fluorinated heterocyclic compounds. 2. 2, 4??difluoro and 4??amino??2??fluoropyrimidines, nucleoside base analogs

PI Svirskaya, V Yedidia, CC Leznoff…

文献索引：Svirskaya, Polina I.; Yedidia, Varda; Leznoff, Clifford C.; Miller, Jack M. Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 149 - 153

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被引用次数: 12

摘要

Abstract Nucleoside base analogs in which fluoro substituents replace the enolic hydroxy groups of uracil, thymine and cytosine have been prepared. Improved methods for the preparation and isolation of the known 2, 4-di-fluoropyrimidine, 2, 4-difluoro-6- methylpyrimidine and the new 2, 4-difluoro-5-methylpyrimidine, 2-fluoro-4-aminopyrimidine, 4-fluoro-2-aminopyrimidine, and other alkylaminofluoropyrimidines are described.