The Journal of organic chemistry

Formation of Pinacol Boronate Esters via Pyridine Iodoborane Hydroboration

AG Karatjas, E Vedejs

文献索引：Karatjas, Andrew G.; Vedejs, Edwin Journal of Organic Chemistry, 2008 , vol. 73, # 23 p. 9508 - 9510

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被引用次数: 12

摘要

Hydroboration of alkenes with pyridine iodoborane followed by treatment with pinacol/NaOH affords monoalkyl pinacol boronates in moderate to good yield. Dialkylborinic acid derivatives are formed competitively, especially in the case of terminal alkenes. This side reaction can be minimized by using excess of pyridine iodoborane. More hindered alkenes give the best results.