The preparation of octahydro leukotrienes C, D, and E via a stereoselective sulfenyllactonization reaction

…, W Coombs, Y Guindon, J Rokach, D Ethier, R Hall

文献索引：Young, Robert N.; Coombs, William; Guindon, Yvan; Rokach, Joshua; Ethier, Diane; Hall, Ronald Tetrahedron Letters, 1981 , vol. 22, # 49 p. 4933 - 4936

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被引用次数: 26

摘要

Abstract Sulfenyl halides derived from the N-trifluoroacetamido methyl ester derivatives of cysteine, cysteinyiglycine and glutathione react stereoselectively with (5E)-and (5Z)- eicosenoic acids to provide, after separation of diastereomers and hydrolysis of the protecting groups, the fully saturated analogues of leukotrienes LTC 4, LTD 4, and LTE 4.