Synthesis and structure-activity relationships of 2-pyridones: a novel series of potent DNA gyrase inhibitors as antibacterial agents

Q Li, DTW Chu, A Claiborne, CS Cooper…

文献索引：Journal of Medicinal Chemistry, , vol. 39, # 16 p. 3070 - 3088

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被引用次数: 81

摘要

... Journal of Medicinal Chemistry. ... The absence of clinically useful drugs for the treatment of VRE strains of bacteria poses a therapeutic challenge to the medical community. The potential spread of this type of resistance to other organisms such as Staph. ...