Practical synthesis of 1, 6-anhydro-2, 4-dideoxy-β-d-glycero-hexopyranos-3-ulose from levoglucosan

…, WR Leonard, DR Bender, DL Hughes

文献索引：Belyk, Kevin M.; Leonard Jr., William R.; Bender, Dean R.; Hughes, David L. Journal of Organic Chemistry, 2000 , vol. 65, # 8 p. 2588 - 2590

全文：HTML全文

被引用次数: 12

摘要

The potential utility of 1, 6-anhydro-2, 4-dideoxyhexopyranoses (eg, 3 and 4, Scheme 1) as chirons in the synthesis of important biologically active compounds has increased interest in developing methods for their preparation. In particular, a number of methods have been described in accounts of the synthesis of precursors to the lactonic portion of mevinic acids, which are potent inhibitors of the enzyme HMG-CoA reductase. 1 The 1, 6-anhydro-2, 4- ...