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In vitro bioactivation of bazedoxifene and 2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol in human liver microsomes

TT Lušin, T Tomašić, J Trontelj, A Mrhar…

文献索引:Chemico-Biological Interactions, , vol. 197, # 1 p. 8 - 15

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被引用次数: 6

摘要

... Chemico-Biological Interactions. Volume 197, Issue 1, 15 April 2012, Pages 8–15. Cover image Cover image. ... Bazedoxifene (II, Fig. 1) is a new, third generation, indole-based estrogen receptor (ER)-ligand developed for use in post-menopausal osteoporosis. ...