The Journal of organic chemistry

… functionalized 7-deazapurine ribonucleosides related to 2-aminoadenosine, guanosine, and xanthosine: Glycosylation of pyrrolo [2, 3-d] pyrimidines with 1-O-acetyl-2, …

F Seela, X Peng

文献索引：Seela, Frank; Peng, Xiaohua Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 81 - 90

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被引用次数: 42

摘要

The Silyl-Hilbert-Johnson reaction as well as the nucleobase-anion glycosylation of a series of 7-deazapurines has been investigated, and the 7-functionalized 7-deazapurine ribonucleosides were prepared. Glycosylation of the 7-halogenated 6-chloro-2- pivaloylamino-7-deazapurines 9b-d with 1-O-acetyl-2, 3, 5-tri-O-benzoyl-d-ribofuranose (5) gave the β-d-nucleosides 11b-d (73-75% yield), which were transformed to a number of ...