One??pot three??component synthesis of 2??substituted 4??aminoquinazolines

K Rad??Moghadam, L Samavi

文献索引：Rad-Moghadam, Kurosh; Samavi, Laleh Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 4 p. 913 - 916

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被引用次数: 12

摘要

The quinazoline ring system is a commonly encountered structural core in a number of natural and synthetic molecules with a wide range of biological activities [1]. Many of the quinazoline derivatives are known to exhibit anti-inflammatory [2], anthelmintic [3], analgesic [4], CNS-depressant [5], and anticonvulsive [6] activities. Metolazone and quinethazone are two quinazoline-based drugs which are used currently as diuretics in medicine [7]. These ...