Pyridazines. XV. Synthesis of 6??aryl??5??amino??3 (2H)??pyridazinones as potential platelet aggregation inhibitors

I Estevez, E Raviña, E Sotelo

文献索引：Estevez, Isabel; Ravina, Enrique; Sotelo, Eddy Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 6 p. 1421 - 1428

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被引用次数: 44

摘要

Abstract Several 3 (2H)-pyridazinones with amino groups at the 5-position of the pyridazine nucleus have been prepared. The 6-aryl-5-halo-3 (2H)-pyridazinones obtained from mucochloric and mucobromic acid lead to the corresponding 5-alkylamino-3 (2H)- pyridazinones, which were tested as platelet aggregation inhibitors.