Tetrahedron letters

Silyl group deprotection by Pd/C/H 2. A facile and selective method

S Kim, SM Jacobo, CT Chang, S Bellone, WS Powell…

文献索引：Kim, Seongjin; Jacobo, Sheila Marie; Chang, Chih-Tsung; Bellone, Sophie; Powell, William S.; Rokach, Joshua Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1973 - 1976

全文：HTML全文

被引用次数: 17

摘要

An easy, high yield, RT, short-reaction-time Pd/C hydrogenation of silyl groups is described. This includes TES, TPS, TBS, TBDMS, TIPS, and TBDPS. The relative selectivity of the process has been investigated and we can show, for example, that TES, TPS, TBS, and TBDMS removal can be performed in the presence of TIPS and TBDPS.