Journal of Asian natural products research

Synthesis and cytotoxic activities of a series of novel N-methyl-bisindolylmaleimide amide derivatives

K Wang, ZZ Liu

文献索引：Wang, Ke; Liu, Zhan-Zhu Journal of Asian Natural Products Research, 2014 , vol. 16, # 3 p. 296 - 303

全文：HTML全文

被引用次数: 0

摘要

A novel series of N-methyl-bisindolylmaleimides were synthesized and evaluated for their inhibitory activities against nine tumor cell lines. Some of the compounds showed an interesting activity against the tested cell lines. The most potent compounds 5e and 5j displayed antiproliferative activity with 50% inhibitory concentration values in the μM range against some tested cell lines.