Tyrosine kinase inhibitors. 16. 6, 5, 6-Tricyclic benzothieno [3, 2-d] pyrimidines and pyrimido [5, 4-b]-and-[4, 5-b] indoles as potent inhibitors of the epidermal growth …

HDH Showalter, AJ Bridges, H Zhou…

文献索引：Journal of Medicinal Chemistry, , vol. 42, # 26 p. 5464 - 5474

全文：HTML全文

被引用次数: 108

摘要

... Journal of Medicinal Chemistry. ... 5,7-10 Although this field started slowly, the discovery of highly selective, ATP-competitive inhibitors based on diarylamines 11 has led to the development of agents with great pharmaceutical potential. ...