Conception and Evolution of Stereocontrolled Strategies toward Functionalized 8-Aryloctanoic Acids Related to the Total Synthesis of Aliskiren

S Hanessian, E Chénard, S Guesné…

文献索引：Takahashi, Taichi; Watanabe, Hidenori; Kitahara, Takeshi Heterocycles, 2002 , vol. 58, p. 99 - 104

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被引用次数: 6

摘要

... Volume: Page ... to the P 2 and P 4 site in the original inhibitors such as CGP-38560 by directly linking P 1 and P 3 (Figure 1). Compared to the previous generation of renin inhibitors, often possessing heterocyclic appendages near ... 4, 3:1, H, G1, Ti(O-i-Pr) 4, 3 d, rt, 58. ...